Journal of the Association of Nurses in AIDS Care
Volume 20, Issue 4 , Pages 326-333 , July 2009

Selenium Supplementation in HIV-Infected Patients: Is There Any Potential Clinical Benefit?

References 

  1. Baum MK, Shor-Posner G, Lai S, Zang G, Lai H, Fletcher MA, et al. High risk of HIV-related mortality is associated with selenium deficiency. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 1997;15:370–374
  2. Burbano X, Miguez-Burbano MJ, McCollister K, Zhang G, Rodriguez A, Ruiz P, et al. Impact of a selenium chemoprevention clinical trial on hospital admissions of HIV-infected participants. HIV Clinical Trials. 2002;3:483–491
  3. Hurwitz BE, Klaus JR, Llabre MM, Gonzalez A, Lawrence PJ, Maher KJ, et al. Suppression of human immunodeficiency virus type 1 viral load with selenium supplementation: A randomized controlled trial. Archives of Internal Medicine. 2007;167:148–154
  4. Kelly P, Musonda R, Kafwembe E, Kaetano L, Keane E, Farthing M. Micronutrient supplementation in AIDS-diarrhoea-wasting syndrome in Zambia: A randomized controlled trial. AIDS. 1999;13:495–500
  5. Kupka R, Msamanga GI, Spiegelman D, Morris S, Mugusi F, Hunter DJ, et al. Selenium status is associated with accelerated disease progression among HIV-1–infected pregnant women in Tanzania. Journal of Nutrition. 2004;134:2556–2560
  6. Look MP, Rockstroh JK, Rao GS, Barton S, Lemoch H, Kaiser R, et al. Sodium selenite and N-acetylcystine in antiretroviral-naive HIV-1 infected patients: A randomized, controlled pilot study. European Journal of Clinical Investigation. 1998;28:389–397
  7. McClelland RS, Baeten JM, Overbaugh J, Richardson BA, Mandaliya K, Emery S, et al. Micronutrient supplementation increases genital tract shedding of HIV-1 in women: Results of a randomized trial. Journal of Acquired Immune Deficiency Syndromes. 2004;37:1657–1663
  8. MedlinePlus. (2008). Selenium (Se). Retrieved November 16, 2008, from http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html
  9. Natural Medicines Comprehensive Database On-line. (2008). Selenium. Retrieved July 18, 2008, from www.naturaldatabase.com
  10. Passaretti C, Gupta A. Selenium and HIV-1: Hope or hype?. Archives of Internal Medicine. 2007;167:2530–2531
  11. Petrie A, Sabin C. Medical statistics at a glance. Malden, MA: Blackwell; 2005;
  12. Range N, Changalucha J, Karaup H, Magnussen P, Andersen AB, Friis H. The effect of multi-vitamin/mineral supplementation on mortality during treatment of pulmonary tuberculosis: A randomized two-by-two factorial trial in Mwanza, Tanzania. British Journal of Nutrition. 2006;95:762–770
  13. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. Selenium: Biochemical role as a component of glutathione peroxidase. Science. 1973;179:588–590
  14. Royal College of Pathologists of Australia Manual 4.0. (2004). Selenium—Blood, plasma. Retrieved November 16, 2008, from http://www.rcpamanual.edu.au/sections/pathologytest.asp?s = 33&i = 585
  15. Shor-Posner G, Lecusay R, Miguez M, Moreno-Black G, Zhang G, Rodriguez N, et al. Psychological burden in the era of HAART: Impact of selenium therapy. International Journal of Psychiatry in Medicine. 2003;33:55–69
  16. Tang AM, Lanzillotti J, Hendricks K, Gerrior J, Ghosh M, Woods M, et al. Micronutrients: Current issues for HIV care providers. AIDS. 2005;19:847–861
  17. Taylor EW, Cox AG, Zhao L, Ruzicka JA, Bhat AA, Zhang WN, et al. Nutrition, HIV, and drug abuse: The molecular basis of a unique role for selenium. Journal of Acquired Immune Deficiency Syndromes. 2000;25(Suppl 1):S53–S61
  18. Zhong L, Holmgren A. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase reveled by characterization of recombinant enzymes with selenocystine mutations. Journal of Biological Chemistry. 2000;24:18121–18128

PII: S1055-3290(09)00066-1

doi: 10.1016/j.jana.2009.03.006

Journal of the Association of Nurses in AIDS Care
Volume 20, Issue 4 , Pages 326-333 , July 2009